Preconditioning of mesenchymal stromal cells with low-intensity ultrasound: influence on chondrogenesis and directed SOX9 signaling pathways

Abstract Background Continuous low-intensity ultrasound (cLIUS) facilitates the chondrogenic differentiation of human mesenchymal stromal cells (MSCs) in the absence of exogenously added transforming growth factor-beta (TGFβ) by upregulating the expression of transcription factor SOX9, a master regu...

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Bibliographic Details
Main Authors: Neety Sahu, Gaurav Budhiraja, Anuradha Subramanian
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Online Access:https://doi.org/10.1186/s13287-019-1532-2