Functional Analysis of p21<sup>Cip1/<i>CDKN1A</i></sup> and Its Family Members in Trophoblastic Cells of the Placenta and Its Roles in Preeclampsia

Functional Analysis of p21<sup>Cip1/<i>CDKN1A</i></sup> and Its Family Members in Trophoblastic Cells of the Placenta and Its Roles in Preeclampsia

Preeclampsia (PE), a gestational hypertensive disease originating from the placenta, is characterized by an imbalance of various cellular processes. The cell cycle regulator p21<sup>Cip1/<i>CDKN1A</i></sup> (p21) and its family members p27 and p57 regulate signaling pathways...

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Bibliographic Details
Main Authors: Nina-Naomi Kreis, Alexandra Friemel, Lukas Jennewein, Samira Catharina Hoock, Anna Elisabeth Hentrich, Thorsten Nowak, Frank Louwen, Juping Yuan
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
p21<sup>Cip1/<i>CDKN1A</i></sup>
trophoblasts
preeclampsia
hypoxia
trophoblast organoids
fusion
Online Access:https://www.mdpi.com/2073-4409/10/9/2214

Internet

https://www.mdpi.com/2073-4409/10/9/2214

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