Hypersynchronous ictal onset in the perirhinal cortex results from dynamic weakening in inhibition

We obtained field, K+ selective and “sharp” intracellular recordings from the rat entorhinal (EC) and perirhinal (PC) cortices in an in vitro brain slice preparation to identify the events occurring at interictal-to-ictal transition during 4-aminopyridine application. Field recordings revealed inter...

Full description

Bibliographic Details
Main Authors: Rüdiger Köhling, Margherita D'Antuono, Ruba Benini, Philip de Guzman, Massimo Avoli
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115301042