Identification of serotype in culture negative pneumococcal meningitis using sequential multiplex PCR: implication for surveillance and vaccine design.

Identification of serotype in culture negative pneumococcal meningitis using sequential multiplex PCR: implication for surveillance and vaccine design.

PCR-based serotyping of Streptococcus pneumoniae has been proposed as a simpler approach than conventional methods, but has not been applied to strains in Asia where serotypes are diverse and different from other part of the world. Furthermore, PCR has not been used to determine serotype distributio...

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Bibliographic Details
Main Authors: Samir K Saha, Gary L Darmstadt, Abdullah H Baqui, Belal Hossain, Maksuda Islam, Dona Foster, Hassan Al-Emran, Aliya Naheed, Shams El Arifeen, Stephen P Luby, Mathuram Santosham, Derrick Crook
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2571985?pdf=render

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http://europepmc.org/articles/PMC2571985?pdf=render

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