Analyses of in vivo interaction and mobility of two spliceosomal proteins using FRAP and BiFC.

U1-70K, a U1 snRNP-specific protein, and serine/arginine-rich (SR) proteins are components of the spliceosome and play critical roles in both constitutive and alternative pre-mRNA splicing. However, the mobility properties of U1-70K, its in vivo interaction with SR proteins, and the mobility of the...

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Bibliographic Details
Main Authors: Gul Shad Ali, K V S K Prasad, M Hanumappa, A S N Reddy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2278372?pdf=render