Impact of Tumor-Derived CCL2 on Macrophage Effector Function

Monocyte chemoattractant protein-1 (MCP-1, CCL2) is produced by many different types of cells. In the current investigation, the effect of tumor-derived CCL2 on macrophages was evaluated to determine the extent to which this chemokine influenced the innate immune response to cancer. To do this, we u...

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Bibliographic Details
Main Authors: M. S. Brault, R. A. Kurt
Format: Article
Language:English
Published: Hindawi Limited 2005-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/JBB.2005.37