Impaired structural motor connectome in amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease selectively affecting upper and lower motor neurons. Patients with ALS suffer from progressive paralysis and eventually die on average after three years. The underlying neurobiology of upper motor neuron degeneration and its e...

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Bibliographic Details
Main Authors: Esther Verstraete, Jan H Veldink, Rene C W Mandl, Leonard H van den Berg, Martijn P van den Heuvel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3166305?pdf=render