Prognostic impact of tumor mutation burden and the mutation in KIAA1211 in small cell lung cancer

Prognostic impact of tumor mutation burden and the mutation in KIAA1211 in small cell lung cancer

Abstract Background Small cell lung cancer (SCLC) is a highly aggressive lung cancer subtype with poor survival and limited treatment options. Sequencing results have revealed gene mutations associated with SCLC, however, the correlation between the genomic alterations and clinical prognosis of SCLC...

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Bibliographic Details
Main Authors: Mengting Zhou, Jun Fan, Zhenyu Li, Pindong Li, Yajie Sun, Yuhui Yang, Xiaoshu Zhou, Jing Wang, Ye Wang, Huiwei Qi, Weijing Cai, Xiaofang Dai, Fred R. Hirsch
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Respiratory Research
Subjects:
Small cell lung cancer
Genomic alterations
Tumor mutation burden
KIAA1211
Overall survival
Progression-free survival
Online Access:http://link.springer.com/article/10.1186/s12931-019-1205-9

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http://link.springer.com/article/10.1186/s12931-019-1205-9

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