Protein aggregates encode epigenetic memory of stressful encounters in individual Escherichia coli cells.

Protein misfolding and aggregation are typically perceived as inevitable and detrimental processes tied to a stress- or age-associated decline in cellular proteostasis. A careful reassessment of this paradigm in the E. coli model bacterium revealed that the emergence of intracellular protein aggrega...

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Bibliographic Details
Main Authors: Sander K Govers, Julien Mortier, Antoine Adam, Abram Aertsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC6112618?pdf=render