Protein aggregates encode epigenetic memory of stressful encounters in individual Escherichia coli cells.
Protein misfolding and aggregation are typically perceived as inevitable and detrimental processes tied to a stress- or age-associated decline in cellular proteostasis. A careful reassessment of this paradigm in the E. coli model bacterium revealed that the emergence of intracellular protein aggrega...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-08-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC6112618?pdf=render |