Quantifying antibiotic impact on within-patient dynamics of extended-spectrum beta-lactamase resistance

Quantifying antibiotic impact on within-patient dynamics of extended-spectrum beta-lactamase resistance

Antibiotic-induced perturbation of the human gut flora is expected to play an important role in mediating the relationship between antibiotic use and the population prevalence of antibiotic resistance in bacteria, but little is known about how antibiotics affect within-host resistance dynamics. Here...

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Bibliographic Details
Main Authors: Rene Niehus, Esther van Kleef, Yin Mo, Agata Turlej-Rogacka, Christine Lammens, Yehuda Carmeli, Herman Goossens, Evelina Tacconelli, Biljana Carevic, Liliana Preotescu, Surbhi Malhotra-Kumar, Ben S Cooper
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
antibiotic resistance
within-host dynamics
resistance carriage
extended-spectrum beta-lactamase
state-space model
gut microbiota
Online Access:https://elifesciences.org/articles/49206

Internet

https://elifesciences.org/articles/49206

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