MITF induces escape from innate immunity in melanoma

MITF induces escape from innate immunity in melanoma

Abstract Background The application of immune-based therapies has revolutionized cancer treatment. Yet how the immune system responds to phenotypically heterogeneous populations within tumors is poorly understood. In melanoma, one of the major determinants of phenotypic identity is the lineage survi...

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Bibliographic Details
Main Authors: Luis Sánchez-del-Campo, Román Martí-Díaz, María F. Montenegro, Rebeca González-Guerrero, Trinidad Hernández-Caselles, Enrique Martínez-Barba, Antonio Piñero-Madrona, Juan Cabezas-Herrera, Colin R. Goding, José Neptuno Rodríguez-López
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
MITF
Melanoma
ADAM10
NK-cells
Anti-tumor immunity
Online Access:https://doi.org/10.1186/s13046-021-01916-8

Internet

https://doi.org/10.1186/s13046-021-01916-8

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