Rare Adult Masseteric Rhabdomyosarcoma and a Review of the Literature

Background: Rhabdomyosarcomas (RMSs) are a group of soft-tissue malignant tumors which derive from primitive skeletal muscle tissue that mainly affect children and adolescents. RMSs are very rare in adults, where they are usually located in the extremities. Case Presentation: A previously healthy 32...

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Main Authors: T. Franco, A. La Boria, R. Domanico, G.L. Piazzetta, G. Donato, E. Allegra
Format: Article
Language:English
Published: Karger Publishers 2013-09-01
Series:Case Reports in Oncology
Subjects:
Online Access:http://www.karger.com/Article/FullText/355250
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spelling doaj-ee3ebd59a334481784562373056cbb232020-11-24T20:48:20ZengKarger PublishersCase Reports in Oncology1662-65752013-09-016347247910.1159/000355250355250Rare Adult Masseteric Rhabdomyosarcoma and a Review of the LiteratureT. FrancoA. La BoriaR. DomanicoG.L. PiazzettaG. DonatoE. AllegraBackground: Rhabdomyosarcomas (RMSs) are a group of soft-tissue malignant tumors which derive from primitive skeletal muscle tissue that mainly affect children and adolescents. RMSs are very rare in adults, where they are usually located in the extremities. Case Presentation: A previously healthy 32-year-old male presented at our ENT (ear, nose and throat) outpatient clinic after experiencing a parotid region swelling for 2 months. The patient was treated surgically by excising the mass and by modified radical ipsilateral neck dissection. Histological and immunohistochemical examination indicated masseteric alveolar RMS with lymphatic metastasis. The patient received radiochemotherapy, and he is still alive with no evidence of disease spread 1 year after diagnosis. Conclusion: This is the first case of a masseter alveolar RMS to be reported in the literature in a patient older than 25 years; it highlights the broad spectrum of neoplasms that cause parotid region swellings and the importance of considering rare tumors during differential diagnosis.http://www.karger.com/Article/FullText/355250Adult rhabdomyosarcomaAlveolar rhabdomyosarcomaHead and neck rhabdomyosarcomaMasseter neoplasm
collection DOAJ
language English
format Article
sources DOAJ
author T. Franco
A. La Boria
R. Domanico
G.L. Piazzetta
G. Donato
E. Allegra
spellingShingle T. Franco
A. La Boria
R. Domanico
G.L. Piazzetta
G. Donato
E. Allegra
Rare Adult Masseteric Rhabdomyosarcoma and a Review of the Literature
Case Reports in Oncology
Adult rhabdomyosarcoma
Alveolar rhabdomyosarcoma
Head and neck rhabdomyosarcoma
Masseter neoplasm
author_facet T. Franco
A. La Boria
R. Domanico
G.L. Piazzetta
G. Donato
E. Allegra
author_sort T. Franco
title Rare Adult Masseteric Rhabdomyosarcoma and a Review of the Literature
title_short Rare Adult Masseteric Rhabdomyosarcoma and a Review of the Literature
title_full Rare Adult Masseteric Rhabdomyosarcoma and a Review of the Literature
title_fullStr Rare Adult Masseteric Rhabdomyosarcoma and a Review of the Literature
title_full_unstemmed Rare Adult Masseteric Rhabdomyosarcoma and a Review of the Literature
title_sort rare adult masseteric rhabdomyosarcoma and a review of the literature
publisher Karger Publishers
series Case Reports in Oncology
issn 1662-6575
publishDate 2013-09-01
description Background: Rhabdomyosarcomas (RMSs) are a group of soft-tissue malignant tumors which derive from primitive skeletal muscle tissue that mainly affect children and adolescents. RMSs are very rare in adults, where they are usually located in the extremities. Case Presentation: A previously healthy 32-year-old male presented at our ENT (ear, nose and throat) outpatient clinic after experiencing a parotid region swelling for 2 months. The patient was treated surgically by excising the mass and by modified radical ipsilateral neck dissection. Histological and immunohistochemical examination indicated masseteric alveolar RMS with lymphatic metastasis. The patient received radiochemotherapy, and he is still alive with no evidence of disease spread 1 year after diagnosis. Conclusion: This is the first case of a masseter alveolar RMS to be reported in the literature in a patient older than 25 years; it highlights the broad spectrum of neoplasms that cause parotid region swellings and the importance of considering rare tumors during differential diagnosis.
topic Adult rhabdomyosarcoma
Alveolar rhabdomyosarcoma
Head and neck rhabdomyosarcoma
Masseter neoplasm
url http://www.karger.com/Article/FullText/355250
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