Construction and applications of rabbit hemorrhagic disease virus replicon.

The study of rabbit hemorrhagic disease virus (RHDV) has long been hindered by the absence of an in vitro culture system. In this study, using RHDV as a model, a series of DNA-based reporter replicons were constructed in which the firefly luciferase (Fluc) gene was fused in-frame with the open readi...

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Bibliographic Details
Main Authors: Binbin Wang, Mingjia Zhe, Zongyan Chen, Chuanfeng Li, Chunchun Meng, Miaotao Zhang, Guangqing Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3648532?pdf=render