Bifunctional quorum-quenching and antibiotic-acylase MacQ forms a 170-kDa capsule-shaped molecule containing spacer polypeptides

Abstract Understanding the molecular mechanisms of bacterial antibiotic resistance will help prepare against further emergence of multi-drug resistant strains. MacQ is an enzyme responsible for the multi-drug resistance of Acidovorax sp. strain MR-S7. MacQ has acylase activity against both N-acylhom...

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Bibliographic Details
Main Authors: Yoshiaki Yasutake, Hiroyuki Kusada, Teppei Ebuchi, Satoshi Hanada, Yoichi Kamagata, Tomohiro Tamura, Nobutada Kimura
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09399-4