Microstructural white matter changes underlying cognitive and behavioural impairment in ALS--an in vivo study using DTI.

Microstructural white matter changes underlying cognitive and behavioural impairment in ALS--an in vivo study using DTI.

BACKGROUND: A relevant fraction of patients with amyotrophic lateral sclerosis (ALS) exhibit a fronto-temporal pattern of cognitive and behavioural disturbances with pronounced deficits in executive functioning and cognitive control of behaviour. Structural imaging shows a decline in fronto-temporal...

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Bibliographic Details
Main Authors: Elisabeth Kasper, Christina Schuster, Judith Machts, Joern Kaufmann, Daniel Bittner, Stefan Vielhaber, Reiner Benecke, Stefan Teipel, Johannes Prudlo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4263750?pdf=render

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http://europepmc.org/articles/PMC4263750?pdf=render

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