gsbDesign: An R Package for Evaluating the Operating Characteristics of a Group Sequential Bayesian Design

gsbDesign: An R Package for Evaluating the Operating Characteristics of a Group Sequential Bayesian Design

The R package gsbDesign provides functions to evaluate the operating characteristics of Bayesian group sequential clinical trial designs. More specifically, we consider clinical trials with interim analyses, which compare a treatment with a control, and where the endpoint is normally distributed. Pr...

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Bibliographic Details
Main Authors: Florian Gerber, Thomas Gsponer
Format: Article
Language:English
Published: Foundation for Open Access Statistics 2016-03-01
Series:Journal of Statistical Software
Subjects:
adaptive design
Bayesian inference
clinical trials
clinical trial monitoring
expected sample size
group sequential design
interim analyses
operating characteristics
stopping criteria
Online Access:https://www.jstatsoft.org/index.php/jss/article/view/2613

Internet

https://www.jstatsoft.org/index.php/jss/article/view/2613

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