The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake
Cytosolic lipid droplets (LDs) are storage organelles for neutral lipids derived from endogenous metabolism. Acyl-CoA synthetase family proteins are essential enzymes in this biosynthetic pathway, contributing activated fatty acids. Fluorescence microscopy showed that ACSL3 is localized to the endop...
Main Authors: | Margarete Poppelreuther, Berenice Rudolph, Chen Du, Regina Großmann, Melanie Becker, Christoph Thiele, Robert Ehehalt, Joachim Füllekrug |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520392191 |
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