Advances, challenges and future directions for stem cell therapy in amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative condition where loss of motor neurons within the brain and spinal cord leads to muscle atrophy, weakness, paralysis and ultimately death within 3–5 years from onset of symptoms. The specific molecular mechanisms...

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Bibliographic Details
Main Authors: Yuri Ciervo, Ke Ning, Xu Jun, Pamela J. Shaw, Richard J. Mead
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13024-017-0227-3