Nanocrystal facet modulation to enhance transferrin binding and cellular delivery

Modulation of exposed crystal facets enhances transferrin binding to chalcogenide nanocrystals and their subsequent delivery into cancer cells. Facet-dependent protein binding occurs through inner-sphere thiol complexation and is affected by the structure of the first solvation shell.

Bibliographic Details
Main Authors: Yu Qi, Tong Zhang, Chuanyong Jing, Sijin Liu, Chengdong Zhang, Pedro J. J. Alvarez, Wei Chen
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14972-z