Sialic acid metabolic engineering: a potential strategy for the neuroblastoma therapy.

Sialic acid metabolic engineering: a potential strategy for the neuroblastoma therapy.

BACKGROUND:Sialic acids (Sia) represent negative-charged terminal sugars on most glycoproteins and glycolipids on the cell surface of vertebrates. Aberrant expression of tumor associated sialylated carbohydrate epitopes significantly increases during onset of cancer. Since Sia contribute towards cel...

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Bibliographic Details
Main Authors: Vinayaga S Gnanapragassam, Kaya Bork, Christina E Galuska, Sebastian P Galuska, Dagobert Glanz, Manimozhi Nagasundaram, Matthias Bache, Dirk Vordermark, Guido Kohla, Christoph Kannicht, Roland Schauer, Rüdiger Horstkorte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4141789?pdf=render

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http://europepmc.org/articles/PMC4141789?pdf=render

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