Treatment of primary axillary hyperhidrosis by fractional microneedle radiofrequency: Is it still effective after long-term follow-up?

Background: Primary axillary hyperhidrosis (PAH) is a chronic idiopathic disorder causing major stress in patients. Among the common therapies for PAH, only surgical interventions have proven feasible as a permanent solution. Objective and Aim: The aim of this study was to evaluate the efficacy and...

Full description

Bibliographic Details
Main Authors: Bahareh Abtahi-Naeini, Farahnaz Fatemi Naeini, Ali Saffaei, Shadi Behfar, Mohsen Pourazizi, Majid Mirmohammadkhani, Najmeh-Sadat Bolandnazar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Indian Journal of Dermatology
Subjects:
Online Access:http://www.e-ijd.org/article.asp?issn=0019-5154;year=2016;volume=61;issue=2;spage=234;epage=234;aulast=Abtahi-Naeini
id doaj-f0036b7729874000b7414a59d85a2a76
record_format Article
spelling doaj-f0036b7729874000b7414a59d85a2a762020-11-24T23:54:33ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112016-01-0161223423410.4103/0019-5154.177789Treatment of primary axillary hyperhidrosis by fractional microneedle radiofrequency: Is it still effective after long-term follow-up?Bahareh Abtahi-NaeiniFarahnaz Fatemi NaeiniAli SaffaeiShadi BehfarMohsen PouraziziMajid MirmohammadkhaniNajmeh-Sadat BolandnazarBackground: Primary axillary hyperhidrosis (PAH) is a chronic idiopathic disorder causing major stress in patients. Among the common therapies for PAH, only surgical interventions have proven feasible as a permanent solution. Objective and Aim: The aim of this study was to evaluate the efficacy and safety of fractional microneedle radiofrequency (FMR) as an alternative permanent treatment for PAH with long-term follow-up. Materials and Methods: This was a single-blind, sham-controlled comparative study. Twenty-five patients with severe PAH were provided three treatments of FMR at 3-week intervals (the treatment group), and a control group was provided the sham treatment. Clinical efficacy was evaluated using the hyperhidrosis disease severity scale (HDSS) at baseline and the end of the study, as well as during the 1 year follow-up phase. Results: HDSS demonstrated significant improvement after treatment in the treatment group compared to the sham control. The mean (±standard deviation) of HDSS in the group being treated with radiofrequency was 2.50 (±0.88) after 1 year follow-up, and that of the control group was 3.38 (±0.49; P < 0.001). Follow-up results show that there were 10 patients (41.6%) with no relapse and 11 patients (45.9%) with relapse after 1 year. There was a significant correlation between HDSS changes in relapse and body mass index (BMI) (P = 0.03). Conclusion: Treatment of PAH with FMR is a safe and noninvasive procedure with a positive therapeutic effect on HDSS. It is recommended, however, that sessions of FMR be repeated after 1 year, particularly in overweight patients with high BMIs. Clinical Trial Registration: IRCT2013111915455N1. Level of Evidences: Level II-1.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2016;volume=61;issue=2;spage=234;epage=234;aulast=Abtahi-NaeiniFractionated microneedle radiofrequencyhyperhidrosis disease severity scaleprimary axillary hyperhidrosis
collection DOAJ
language English
format Article
sources DOAJ
author Bahareh Abtahi-Naeini
Farahnaz Fatemi Naeini
Ali Saffaei
Shadi Behfar
Mohsen Pourazizi
Majid Mirmohammadkhani
Najmeh-Sadat Bolandnazar
spellingShingle Bahareh Abtahi-Naeini
Farahnaz Fatemi Naeini
Ali Saffaei
Shadi Behfar
Mohsen Pourazizi
Majid Mirmohammadkhani
Najmeh-Sadat Bolandnazar
Treatment of primary axillary hyperhidrosis by fractional microneedle radiofrequency: Is it still effective after long-term follow-up?
Indian Journal of Dermatology
Fractionated microneedle radiofrequency
hyperhidrosis disease severity scale
primary axillary hyperhidrosis
author_facet Bahareh Abtahi-Naeini
Farahnaz Fatemi Naeini
Ali Saffaei
Shadi Behfar
Mohsen Pourazizi
Majid Mirmohammadkhani
Najmeh-Sadat Bolandnazar
author_sort Bahareh Abtahi-Naeini
title Treatment of primary axillary hyperhidrosis by fractional microneedle radiofrequency: Is it still effective after long-term follow-up?
title_short Treatment of primary axillary hyperhidrosis by fractional microneedle radiofrequency: Is it still effective after long-term follow-up?
title_full Treatment of primary axillary hyperhidrosis by fractional microneedle radiofrequency: Is it still effective after long-term follow-up?
title_fullStr Treatment of primary axillary hyperhidrosis by fractional microneedle radiofrequency: Is it still effective after long-term follow-up?
title_full_unstemmed Treatment of primary axillary hyperhidrosis by fractional microneedle radiofrequency: Is it still effective after long-term follow-up?
title_sort treatment of primary axillary hyperhidrosis by fractional microneedle radiofrequency: is it still effective after long-term follow-up?
publisher Wolters Kluwer Medknow Publications
series Indian Journal of Dermatology
issn 0019-5154
1998-3611
publishDate 2016-01-01
description Background: Primary axillary hyperhidrosis (PAH) is a chronic idiopathic disorder causing major stress in patients. Among the common therapies for PAH, only surgical interventions have proven feasible as a permanent solution. Objective and Aim: The aim of this study was to evaluate the efficacy and safety of fractional microneedle radiofrequency (FMR) as an alternative permanent treatment for PAH with long-term follow-up. Materials and Methods: This was a single-blind, sham-controlled comparative study. Twenty-five patients with severe PAH were provided three treatments of FMR at 3-week intervals (the treatment group), and a control group was provided the sham treatment. Clinical efficacy was evaluated using the hyperhidrosis disease severity scale (HDSS) at baseline and the end of the study, as well as during the 1 year follow-up phase. Results: HDSS demonstrated significant improvement after treatment in the treatment group compared to the sham control. The mean (±standard deviation) of HDSS in the group being treated with radiofrequency was 2.50 (±0.88) after 1 year follow-up, and that of the control group was 3.38 (±0.49; P < 0.001). Follow-up results show that there were 10 patients (41.6%) with no relapse and 11 patients (45.9%) with relapse after 1 year. There was a significant correlation between HDSS changes in relapse and body mass index (BMI) (P = 0.03). Conclusion: Treatment of PAH with FMR is a safe and noninvasive procedure with a positive therapeutic effect on HDSS. It is recommended, however, that sessions of FMR be repeated after 1 year, particularly in overweight patients with high BMIs. Clinical Trial Registration: IRCT2013111915455N1. Level of Evidences: Level II-1.
topic Fractionated microneedle radiofrequency
hyperhidrosis disease severity scale
primary axillary hyperhidrosis
url http://www.e-ijd.org/article.asp?issn=0019-5154;year=2016;volume=61;issue=2;spage=234;epage=234;aulast=Abtahi-Naeini
work_keys_str_mv AT baharehabtahinaeini treatmentofprimaryaxillaryhyperhidrosisbyfractionalmicroneedleradiofrequencyisitstilleffectiveafterlongtermfollowup
AT farahnazfateminaeini treatmentofprimaryaxillaryhyperhidrosisbyfractionalmicroneedleradiofrequencyisitstilleffectiveafterlongtermfollowup
AT alisaffaei treatmentofprimaryaxillaryhyperhidrosisbyfractionalmicroneedleradiofrequencyisitstilleffectiveafterlongtermfollowup
AT shadibehfar treatmentofprimaryaxillaryhyperhidrosisbyfractionalmicroneedleradiofrequencyisitstilleffectiveafterlongtermfollowup
AT mohsenpourazizi treatmentofprimaryaxillaryhyperhidrosisbyfractionalmicroneedleradiofrequencyisitstilleffectiveafterlongtermfollowup
AT majidmirmohammadkhani treatmentofprimaryaxillaryhyperhidrosisbyfractionalmicroneedleradiofrequencyisitstilleffectiveafterlongtermfollowup
AT najmehsadatbolandnazar treatmentofprimaryaxillaryhyperhidrosisbyfractionalmicroneedleradiofrequencyisitstilleffectiveafterlongtermfollowup
_version_ 1725465880011210752