Synergistic Apoptotic Effect Of Indole-3-Carbinol And Doxorubicin On Pre-B Acute Lymphoblastic Leukemia Cells
Background and Aim: Indole-3-carbinol (I3C), found in Brassica species vegetables, exhibits antitumor effects. It has been shown that I3C induces apoptosis in various cell types through inactivation of the nuclear factor-kappa B (NF- k B) pathway. Anthracyclines such as doxorubicin, is widely used i...
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Tehran University of Medical Sciences