Synergistic Apoptotic Effect Of Indole-3-Carbinol And Doxorubicin On Pre-B Acute Lymphoblastic Leukemia Cells

Background and Aim: Indole-3-carbinol (I3C), found in Brassica species vegetables, exhibits antitumor effects. It has been shown that I3C induces apoptosis in various cell types through inactivation of the nuclear factor-kappa B (NF- k B) pathway. Anthracyclines such as doxorubicin, is widely used i...

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Bibliographic Details
Main Authors: Behnaz Tavasoli, Majid Safa, Ahmad Kazemi
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2015-01-01
Series:پیاورد سلامت
Subjects:
i3c
Online Access:http://payavard.tums.ac.ir/article-1-5529-en.html