Mycoplasma suppression of THP-1 Cell TLR responses is corrected with antibiotics.

Mycoplasma contamination of cultured cell lines is a serious problem in research, altering cellular response to different stimuli thus compromising experimental results. We found that chronic mycoplasma contamination of THP-1 cells suppresses responses of THP-1 cells to TLR stimuli. For example, E....

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Bibliographic Details
Main Authors: Ekaterina Zakharova, Jaykumar Grandhi, Mark D Wewers, Mikhail A Gavrilin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2845629?pdf=render