A Novel Antigen-Sampling Cell in the Teleost Gill Epithelium With the Potential for Direct Antigen Presentation in Mucosal Tissue

A Novel Antigen-Sampling Cell in the Teleost Gill Epithelium With the Potential for Direct Antigen Presentation in Mucosal Tissue

In mammals, M cells can take up antigens through mucosal surfaces of the gut and the respiratory tract. Since M cells are deficient of lysosomes and phagosomes, the antigens are directly delivered to the mucosa-associated lymphoid tissue (MALT) without degradation. In teleost fish, the entire body s...

Full description

Bibliographic Details
Main Authors: Goshi Kato, Haruya Miyazawa, Yumiko Nakayama, Yuki Ikari, Hidehiro Kondo, Takuya Yamaguchi, Motohiko Sano, Uwe Fischer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
Oncorhynchus mykiss
comparative immunology
mucosal vaccination
atypical antigen presenting cell
lower vertebrate
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02116/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02116/full

Similar Items