Nanog Signaling Mediates Radioresistance in ALDH-Positive Breast Cancer Cells

Recently, cancer stem cells (CSCs) have been identified as the major cause of both chemotherapy and radiotherapy resistance. Evidence from experimental studies applying both in vitro and in vivo preclinical models suggests that CSCs survive after conventional therapy protocols. Several mechanisms ar...

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Bibliographic Details
Main Authors: Mozhgan Dehghan Harati, H. Peter Rodemann, Mahmoud Toulany
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
Akt
Online Access:http://www.mdpi.com/1422-0067/20/5/1151