Indole-4-carboxaldehyde Isolated from Seaweed, <i>Sargassum thunbergii</i>, Attenuates Methylglyoxal-Induced Hepatic Inflammation

Glucose degradation is aberrantly increased in hyperglycemia, which causes various harmful effects on the liver. Glyoxalase-1 (Glo-1) is a ubiquitous cellular enzyme that participates in the detoxification of methylglyoxal (MGO), a cytotoxic byproduct of glycolysis that induces protein modification...

Full description

Bibliographic Details
Main Authors: Seon-Heui Cha, Yongha Hwang, Soo-Jin Heo, Hee-Sook Jun
Format: Article
Published: MDPI AG 2019-08-01
Series:Marine Drugs
Online Access: