The miR-204-5p/FOXC1/GDF7 axis regulates the osteogenic differentiation of human adipose-derived stem cells via the AKT and p38 signalling pathways

The miR-204-5p/FOXC1/GDF7 axis regulates the osteogenic differentiation of human adipose-derived stem cells via the AKT and p38 signalling pathways

Abstract Background Human adipose-derived stem cells (hADSCs) are stem cells with the potential to differentiate in multiple directions. miR-204-5p is expressed at low levels during the osteogenic differentiation of hADSCs, and its specific regulatory mechanism remains unclear. Here, we aimed to exp...

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Bibliographic Details
Main Authors: You Zhou, Siyu Liu, Wei Wang, Qiang Sun, Mengzhu Lv, Shude Yang, Shuang Tong, Shu Guo
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Human adipose-derived stem cells
Osteogenic differentiation
miR-204-5p
Forkhead box C1
Growth differentiation factor 7
Online Access:https://doi.org/10.1186/s13287-020-02117-4

Internet

https://doi.org/10.1186/s13287-020-02117-4

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