Hepatocyte SHP-1 is a Critical Modulator of Inflammation During Endotoxemia

Abstract Liver hepatocytes (Hep) are known to be central players during the inflammatory response to systemic infection. Interestingly, the protein tyrosine phosphatases (PTP) SHP-1, has been recognized as a major regulator of inflammation; however their implication in the control of Hep-mediated in...

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Bibliographic Details
Main Authors: Anupam Adhikari, Caroline Martel, André Marette, Martin Olivier
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02512-7