The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1

The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1

Summary: Histone variants complement and integrate histone post-translational modifications in regulating transcription. The histone variant macroH2A1 (mH2A1) is almost three times the size of its canonical H2A counterpart, due to the presence of an ∼25 kDa evolutionarily conserved non-histone macro...

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Bibliographic Details
Main Authors: Stefania Dell’Orso, A. Hongjun Wang, Han-Yu Shih, Kayoko Saso, Libera Berghella, Gustavo Gutierrez-Cruz, Andreas G. Ladurner, John J. O’Shea, Vittorio Sartorelli, Hossein Zare
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716000036

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