Ferroptosis and Cancer: Mitochondria Meet the “Iron Maiden” Cell Death

Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent lipid peroxidation. As major sites of iron utilization and master regulators of oxidative metabolism, mitochondria are the main source of reactive oxygen species (ROS) and, thus, play a role in this type of RC...

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Bibliographic Details
Main Authors: Anna Martina Battaglia, Roberta Chirillo, Ilenia Aversa, Alessandro Sacco, Francesco Costanzo, Flavia Biamonte
Format: Article
Published: MDPI AG 2020-06-01
Online Access:https://www.mdpi.com/2073-4409/9/6/1505