The Expression of the Short Isoform of Thymic Stromal Lymphopoietin in the Colon Is Regulated by the Nuclear Receptor Peroxisome Proliferator Activated Receptor-Gamma and Is Impaired during Ulcerative Colitis

The Expression of the Short Isoform of Thymic Stromal Lymphopoietin in the Colon Is Regulated by the Nuclear Receptor Peroxisome Proliferator Activated Receptor-Gamma and Is Impaired during Ulcerative Colitis

The etiology of inflammatory bowel diseases remains largely unknown. We previously demonstrated that the expression of the peroxisome proliferator activated receptor-gamma (PPARγ) is downregulated in colonic epithelial cells of patients with ulcerative colitis (UC). PPARγ is a nuclear receptor that...

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Bibliographic Details
Main Authors: Anthony Martin Mena, Audrey Langlois, Silvia Speca, Lucil Schneider, Pierre Desreumaux, Laurent Dubuquoy, Benjamin Bertin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
PPARgamma
thymic stromal lymphopoietin
intestinal epithelial cells
ulcerative colitis
colon
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01052/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01052/full

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