Non-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based study
Abstract Background Hypertension is a challenging public health problem with a huge burden in the developing countries. Non-adherence to antihypertensive treatment is a big obstacle in blood pressure (BP) control and favours disease progression to complications. Our objectives were to determine the...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
|
Series: | BMC Cardiovascular Disorders |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12872-018-0888-z |
id |
doaj-f1646c4c69134c26b287e1e003dde6ba |
---|---|
record_format |
Article |
spelling |
doaj-f1646c4c69134c26b287e1e003dde6ba2020-11-25T03:47:13ZengBMCBMC Cardiovascular Disorders1471-22612018-07-011811910.1186/s12872-018-0888-zNon-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based studyNkengla Menka Adidja0Valirie Ndip Agbor1Jeannine A. Aminde2Calypse A. Ngwasiri3Kathleen Blackett Ngu4Leopold Ndemnge Aminde5Faculty of Health Sciences, University of BueaIbal Sub-divisional HospitalFaculty of Health Sciences, University of BueaBamendjou District HospitalFaculty of Medicine & Biomedical Sciences, University of Yaoundé 1Faculty of Medicine, School of Public Health, The University of QueenslandAbstract Background Hypertension is a challenging public health problem with a huge burden in the developing countries. Non-adherence to antihypertensive treatment is a big obstacle in blood pressure (BP) control and favours disease progression to complications. Our objectives were to determine the rate of non-adherence to antihypertensive pharmacotherapy, investigate factors associated with non-adherence, and to assess the association between non-adherence and BP control in the Buea Health District (BHD), Cameroon. Methods A community-based cross-sectional study using stratified cluster sampling was conducted in the BHD from November 2013 – March 2014. Eligible consenting adult participants had their BP measured and classified using the Joint National Committee VII criteria. The Morisky medication adherence scale was used to assess adherence to BP lowering medication. Multivariable logistic regression models were used to predict non-adherence. Results One hundred and eighty-three participants were recruited with mean age of 55.9 years. Overall, 67.7% (95% CI: 59.8–73.6%) of participants were non-adherent to their medications. After adjusting for age, sex and other covariates, forgetfulness (aOR = 7.9, 95%CI: 3.0–20.8), multiple daily doses (aOR = 2.5, 95%CI: 1.2–5.6), financial constraints (aOR = 2.8, 95%CI: 1.1–6.9) and adverse drug effects (aOR = 7.6, 95%CI: 1.7–33.0) independently predicted non-adherence to anti-hypertensive medication. BP was controlled in only 21.3% of participants and was better in those who were adherent to medication (47.5% versus 8.2%, p < 0.01). Conclusion At least two of every three hypertensive patients in the Buea Health District are non-adherent to treatment. Forgetfulness, multiple daily doses of medication, financial constraints and medication adverse effects are the major predictors of non-adherence in hypertensive patients. These factors should be targeted to improve adherence and BP control, which will contribute to stem hypertension-related morbidity and mortality.http://link.springer.com/article/10.1186/s12872-018-0888-zHypertensionMedication adherenceNon-adherenceMorisky scaleCameroon |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nkengla Menka Adidja Valirie Ndip Agbor Jeannine A. Aminde Calypse A. Ngwasiri Kathleen Blackett Ngu Leopold Ndemnge Aminde |
spellingShingle |
Nkengla Menka Adidja Valirie Ndip Agbor Jeannine A. Aminde Calypse A. Ngwasiri Kathleen Blackett Ngu Leopold Ndemnge Aminde Non-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based study BMC Cardiovascular Disorders Hypertension Medication adherence Non-adherence Morisky scale Cameroon |
author_facet |
Nkengla Menka Adidja Valirie Ndip Agbor Jeannine A. Aminde Calypse A. Ngwasiri Kathleen Blackett Ngu Leopold Ndemnge Aminde |
author_sort |
Nkengla Menka Adidja |
title |
Non-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based study |
title_short |
Non-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based study |
title_full |
Non-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based study |
title_fullStr |
Non-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based study |
title_full_unstemmed |
Non-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based study |
title_sort |
non-adherence to antihypertensive pharmacotherapy in buea, cameroon: a cross-sectional community-based study |
publisher |
BMC |
series |
BMC Cardiovascular Disorders |
issn |
1471-2261 |
publishDate |
2018-07-01 |
description |
Abstract Background Hypertension is a challenging public health problem with a huge burden in the developing countries. Non-adherence to antihypertensive treatment is a big obstacle in blood pressure (BP) control and favours disease progression to complications. Our objectives were to determine the rate of non-adherence to antihypertensive pharmacotherapy, investigate factors associated with non-adherence, and to assess the association between non-adherence and BP control in the Buea Health District (BHD), Cameroon. Methods A community-based cross-sectional study using stratified cluster sampling was conducted in the BHD from November 2013 – March 2014. Eligible consenting adult participants had their BP measured and classified using the Joint National Committee VII criteria. The Morisky medication adherence scale was used to assess adherence to BP lowering medication. Multivariable logistic regression models were used to predict non-adherence. Results One hundred and eighty-three participants were recruited with mean age of 55.9 years. Overall, 67.7% (95% CI: 59.8–73.6%) of participants were non-adherent to their medications. After adjusting for age, sex and other covariates, forgetfulness (aOR = 7.9, 95%CI: 3.0–20.8), multiple daily doses (aOR = 2.5, 95%CI: 1.2–5.6), financial constraints (aOR = 2.8, 95%CI: 1.1–6.9) and adverse drug effects (aOR = 7.6, 95%CI: 1.7–33.0) independently predicted non-adherence to anti-hypertensive medication. BP was controlled in only 21.3% of participants and was better in those who were adherent to medication (47.5% versus 8.2%, p < 0.01). Conclusion At least two of every three hypertensive patients in the Buea Health District are non-adherent to treatment. Forgetfulness, multiple daily doses of medication, financial constraints and medication adverse effects are the major predictors of non-adherence in hypertensive patients. These factors should be targeted to improve adherence and BP control, which will contribute to stem hypertension-related morbidity and mortality. |
topic |
Hypertension Medication adherence Non-adherence Morisky scale Cameroon |
url |
http://link.springer.com/article/10.1186/s12872-018-0888-z |
work_keys_str_mv |
AT nkenglamenkaadidja nonadherencetoantihypertensivepharmacotherapyinbueacameroonacrosssectionalcommunitybasedstudy AT valiriendipagbor nonadherencetoantihypertensivepharmacotherapyinbueacameroonacrosssectionalcommunitybasedstudy AT jeannineaaminde nonadherencetoantihypertensivepharmacotherapyinbueacameroonacrosssectionalcommunitybasedstudy AT calypseangwasiri nonadherencetoantihypertensivepharmacotherapyinbueacameroonacrosssectionalcommunitybasedstudy AT kathleenblackettngu nonadherencetoantihypertensivepharmacotherapyinbueacameroonacrosssectionalcommunitybasedstudy AT leopoldndemngeaminde nonadherencetoantihypertensivepharmacotherapyinbueacameroonacrosssectionalcommunitybasedstudy |
_version_ |
1724502946758000640 |