DNA methylation of the serotonin transporter gene in peripheral cells and stress-related changes in hippocampal volume: a study in depressed patients and healthy controls.

Serotonin plays an important role in the etiology of depression. Serotonin is also crucial for brain development. For instance, animal studies have demonstrated that early disruptions in the serotonin system affect brain development and emotion regulation in later life. A plausible explanation is th...

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Bibliographic Details
Main Authors: Linda Booij, Moshe Szyf, Angela Carballedo, Eva-Maria Frey, Derek Morris, Sergiy Dymov, Farida Vaisheva, Victoria Ly, Ciara Fahey, James Meaney, Michael Gill, Thomas Frodl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4363605?pdf=render