Non-Covalent Synthesis of Metal Oxide Nanoparticle–Heparin Hybrid Systems: A New Approach to Bioactive Nanoparticles

Heparin has been conjugated to Fe3O4, Co3O4, and NiO nanoparticles (NPs) through electrostatic interactions, producing colloidal suspensions of hybrid metal oxide heparin NPs that are stable in water. Negative zeta potentials and retention of heparin’s ability to capture toluidine blue indicate that...

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Bibliographic Details
Main Authors: Giorgio Eisele, Rosalba Gornati, Giovanni Bernardini, Sabrina Bertini, Giangiacomo Torri, Alessia Coletti, Elena Vismara, Antonio Valerio
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/14/7/13463