Pax6 Lengthens G1 Phase and Decreases Oscillating Cdk6 Levels in Murine Embryonic Cortical Progenitors

Pax6 is a key regulator of the rates of progenitor cell division in cerebral corticogenesis. Previous work has suggested that this action is mediated at least in part by regulation of the cell cycle gene Cdk6, which acts largely on the transition from G1 to S phase. We began the present study by inv...

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Bibliographic Details
Main Authors: Da Mi, Martine Manuel, Yu-Ting Huang, John O. Mason, David J. Price
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular Neuroscience
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Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00419/full

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