Dendritic/Post-synaptic Tau and Early Pathology of Alzheimer’s Disease

Microtubule-associated protein tau forms insoluble neurofibrillary tangles (NFTs), which is one of the major histopathological hallmarks of Alzheimer’s disease (AD). Many studies have demonstrated that tau causes early functional deficits prior to the formation of neurofibrillary aggregates. The red...

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Bibliographic Details
Main Authors: Xiaomin Yin, Chenhao Zhao, Yanyan Qiu, Zheng Zhou, Junze Bao, Wei Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
tau
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.671779/full