Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina.

Analysis of transcriptional regulatory pathways of photoreceptor genes by expression profiling of the Otx2-deficient retina.

In the vertebrate retina, the Otx2 transcription factor plays a crucial role in the cell fate determination of both rod and cone photoreceptors. We previously reported that Otx2 conditional knockout (CKO) mice exhibited a total absence of rods and cones in the retina due to their cell fate conversio...

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Bibliographic Details
Main Authors: Yoshihiro Omori, Kimiko Katoh, Shigeru Sato, Yuki Muranishi, Taro Chaya, Akishi Onishi, Takashi Minami, Takashi Fujikado, Takahisa Furukawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3094341?pdf=render

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http://europepmc.org/articles/PMC3094341?pdf=render

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