Genetic Underpinnings of Increased BMI and Its Association With Late Midlife Cognitive Abilities

Objectives: First, we test for differences in various cognitive abilities across trajectories of body mass index (BMI) over the later life course. Second, we examine whether genetic risk factors for unhealthy BMIs—assessed via polygenic risk scores (PRS)—predict cognitive abilities in late-life. Met...

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Bibliographic Details
Main Authors: Hong Xian PhD, Brian Boutwell PhD, Chandra A. Reynolds PhD, Daphne Lew MPH, Mark Logue PhD, Daniel E. Gustavson PhD, Nicholas Kavish MA, Matthew S. Panizzon PhD, Xin Tu PhD, Rosemary Toomey PhD, Olivia K. Puckett BS, Jeremy A. Elman PhD, Kristen C. Jacobson PhD, Michael J. Lyons PhD, William S. Kremen PhD, Carol E. Franz PhD
Format: Article
Language:English
Published: SAGE Publishing 2020-05-01
Series:Gerontology and Geriatric Medicine
Online Access:https://doi.org/10.1177/2333721420925267