Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice—a model of familial Parkinson's disease

Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice—a model of familial Parkinson's disease

Parkinson's disease (PD) is the most common neurodegenerative movement disorder and is characterized by the loss of dopaminergic neurons in the substantia nigra compacta. α-Synuclein is strongly implicated in the pathophysiology of PD because aggregated α-synuclein accumulates in the brains of...

Full description

Bibliographic Details
Main Authors: H. Fai Poon, Mark Frasier, Nathan Shreve, Vittorio Calabrese, Benjamin Wolozin, D. Allan Butterfield
Format: Article
Language:English
Published: Elsevier 2005-04-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
A30P
Oxidative stress
Lactate dehydrogenase
Enolase
Carbonic anhydrase
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104003201

Internet

http://www.sciencedirect.com/science/article/pii/S0969996104003201

Similar Items