Immune parameters to consider when choosing T-cell receptors for therapy

T-cell receptor (TCR) therapy has arrived as a realistic treatment option for many human diseases. TCR gene therapy allows for the mass redirection of T-cells against a defined antigen while high affinity TCR engineering allows for the creation of a new class of soluble drugs. However, deciding whic...

Full description

Bibliographic Details
Main Authors: John J Miles, Scott R Burrows
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00229/full