The P4-ATPase ATP9A is a novel determinant of exosome release.

Extracellular vesicles (EVs) released by cells have a role in intercellular communication to regulate a wide range of biological processes. Two types of EVs can be recognized. Exosomes, which are released from multi-vesicular bodies upon fusion with the plasma membrane, and ectosomes, which directly...

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Main Authors: Jyoti Naik, Chi M Hau, Lysbeth Ten Bloemendaal, Kam S Mok, Najat Hajji, Ann M Wehman, Sander Meisner, Vanesa Muncan, Nanne J Paauw, H E de Vries, Rienk Nieuwland, Coen C Paulusma, Piter J Bosma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213069