Shorter Leukocyte Telomere Length Is Associated with Worse Survival of Patients with Bladder Cancer and Renal Cell Carcinoma

Shorter Leukocyte Telomere Length Is Associated with Worse Survival of Patients with Bladder Cancer and Renal Cell Carcinoma

Background: Telomeres are protein–DNA complexes at the tips of linear chromosomes. They protect the DNA from end-to-end fusion and exonucleolytic degradation. Shortening of telomeric DNA during aging can generate dysfunctional telomeres, promoting tumorigenesis. More recent data indicate that both s...

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Bibliographic Details
Main Authors: Xi Zheng, Felix Wezel, Anca Azoitei, Sabine Meessen, Wenya Wang, Gregoire Najjar, Xue Wang, Johann M. Kraus, Hans A. Kestler, Axel John, Friedemann Zengerling, Christian Bolenz, Cagatay Günes
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
bladder cancer
renal cell carcinoma
leukocyte
telomere
telomerase
Online Access:https://www.mdpi.com/2072-6694/13/15/3774

Internet

https://www.mdpi.com/2072-6694/13/15/3774

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