Long Non-coding RNA GAS5 Maintains Insulin Secretion by Regulating Multiple miRNAs in INS-1 832/13 Cells

Long Non-coding RNA GAS5 Maintains Insulin Secretion by Regulating Multiple miRNAs in INS-1 832/13 Cells

Type-2 diabetes mellitus (T2DM) is a complex disease characterized by reduced pancreatic islets β-cell mass and impaired insulin release from these cells. Non-coding RNAs, including microRNAs (miRNA) and long non-coding RNAs (lncRNAs), play a role in the progression of T2DM. Decreased serum lncRNA G...

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Bibliographic Details
Main Authors: Yanwei Luo, Jie Guo, Pingsheng Xu, Rong Gui
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
gene therapy
GAS5
insulin secretion
long non-coding RNA
type-2 diabetes
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.559267/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2020.559267/full

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