Is There a Synergistic Effect of Topical Plus Intravenous Tranexamic Acid Versus Intravenous Administration Alone on Blood Loss and Transfusions in Primary Total Hip and Knee Arthroplasties?

Is There a Synergistic Effect of Topical Plus Intravenous Tranexamic Acid Versus Intravenous Administration Alone on Blood Loss and Transfusions in Primary Total Hip and Knee Arthroplasties?

Background: The optimal route and dosing regimen of tranexamic acid (TXA) in primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) remain unclear. As such, we sought to analyze if there was a synergistic effect of intravenous (IV) and topical TXA on blood loss and transfusions. Meth...

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Bibliographic Details
Main Authors: Brian P. Chalmers, MD, Mithun Mishu, BA, Fred D. Cushner, MD, Peter K. Sculco, MD, Joseph Nguyen, BS, Geoffrey H. Westrich, MD
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Arthroplasty Today
Subjects:
Blood loss
Tranexamic acid (TXA)
Blood transfusion
Total hip
Total knee
Online Access:http://www.sciencedirect.com/science/article/pii/S2352344120302624

Internet

http://www.sciencedirect.com/science/article/pii/S2352344120302624

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