Stereological study of octreotide’s (somatostatin analogue) chronic effects on the prevention of glomerular mesangial expansion in uninephrectomized diabetic rats
Background: Diabetic nephropathy is one of the causes of end stage renal diseases (ESRD). Increase of IGF-1(insulin like growth factor) and GH (growth hormone) in diabetes induce kidney lesions especially Intraglomerular mesangial expansion, glomerular sclerosis and finally nephron dysfunction. In t...
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Lorestan University of Medical Science