Chaotic activation of developmental signalling pathways drives idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is characterised by an important remodelling of lung parenchyma. Current evidence indicates that the disease is triggered by alveolar epithelium activation following chronic lung injury, resulting in alveolar epithelial type 2 cell hyperplasia and bronchiolisation...

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Bibliographic Details
Main Authors: Antoine Froidure, Emmeline Marchal-Duval, Meline Homps-Legrand, Mada Ghanem, Aurélien Justet, Bruno Crestani, Arnaud Mailleux
Format: Article
Language:English
Published: European Respiratory Society 2020-11-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/29/158/190140.full