Network analysis reveals essential proteins that regulate sodium-iodide symporter expression in anaplastic thyroid carcinoma

Abstract Anaplastic thyroid carcinoma (ATC) is the most rare and lethal form of thyroid cancer and requires effective treatment. Efforts have been made to restore sodium-iodide symporter (NIS) expression in ATC cells where it has been downregulated, yet without complete success. Systems biology appr...

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Bibliographic Details
Main Authors: Hassan Rakhsh-Khorshid, Hilda Samimi, Shukoofeh Torabi, Sayed Mahmoud Sajjadi-Jazi, Hamed Samadi, Fatemeh Ghafouri, Yazdan Asgari, Vahid Haghpanah
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78574-x