Abstract OR-2: Investigating Interaction of Pioneering Transcription Factors with Nucleosomes Using Cryo-Electron Microscopy

Background: Specific regulation of gene expression determines cellular life and fate. Hundreds of transcription factor proteins (TFs) play critical role in this process. Typically, TFs bind short DNA motifs and then alter expression of their target genes. Majority of cellular DNA is associated with...

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Bibliographic Details
Main Authors: Svetlana Dodonova, Patrick Cramer
Format: Article
Language:English
Published: International Medical Research and Development Corporation 2019-06-01
Series:International Journal of Biomedicine
Subjects:
Online Access:http://ijbm.org/articles/IJBM_2019_9_S1_OR2.pdf