Platelets Guide Leukocytes to Their Sites of Extravasation.

Effective immune responses require the directed migration of leukocytes from the vasculature to the site of injury or infection. How immune cells "find" their site of extravasation remains largely obscure. Here, we identified a previously unrecognized role of platelets as pathfinders guidi...

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Bibliographic Details
Main Authors: Gabriele Zuchtriegel, Bernd Uhl, Daniel Puhr-Westerheide, Michaela Pörnbacher, Kirsten Lauber, Fritz Krombach, Christoph Andreas Reichel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4859536?pdf=render